However, our understanding of CVD i

However, our understanding of CVD in T1DM comes in large
part from the previous era of less intensive glycemic control. More intensive glyce-
mic control is associated with significant risk of weight gain, which may be magnified
by the obesity epidemic. There is growing interest in better understanding the
adverse effects of glycemia, the prevalence and type of lipid abnormalities in
T1DM, the prognostic role of albuminuria and renal insufficiency, and the role of
blood pressure (BP) in CVD. Obesity-associated metabolic abnormalities such as the
proinflammatory state likely modify CVD risk in T1DM; however, the effect may be
different from what is seen in T2DM. These concepts, and how they may affect
management, have not been fully explored

Hasil (Bahasa Indonesia) 2:

Namun, pemahaman kita tentang CVD di T1DM datang dalam jumlah besar
bagian dari era sebelumnya kurang kontrol glikemik intensif. Lebih intensif glyce-
kontrol mic dikaitkan dengan risiko yang signifikan dari berat badan, yang mungkin Magni fi ed
oleh epidemi obesitas. Ada minat yang tumbuh di lebih memahami
efek samping dari glikemia, prevalensi dan jenis kelainan lipid di
T1DM, peran prognostik albuminuria dan ginjal insufisiensi, dan peran
tekanan darah (BP) di CVD. Kelainan metabolik obesitas-terkait seperti
proin fl negara peradangan kemungkinan memodifikasi risiko CVD di T1DM; Namun, efeknya mungkin
berbeda dari apa yang terlihat di DMT2. Konsep-konsep ini, dan bagaimana mereka dapat mempengaruhi
manajemen, belum sepenuhnya dieksplorasi