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In addition, the alterations in neurohormones such asghrelin and leptin may be involved in the pathophysiologyof SAD. This can result in hyperphagia, with cravings forcarbohydrates, and subsequently, can contribute to amoderate weight gain that frequently accompaniesdepressive and obsessive–compulsive disorders, whichmight favorably respond to BLT (Cizza et al.2005; Garaulet et al.2011).According to the clinical observations by PraschakRieder and Willeit (2003), the morning BLT may besuperior to the evening one, since it reduces the secretionof melatonin in phase-shift delay. The duration and frequency of BLT exposure are still controversial (Kronfeld-Schor and Einat 2012). For instance, Reeves et al.(2012) reported that a significant improvement in thedepression scores can be found even after a single BLTsession.
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