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DiscussionThe complex chemistry and physiology of the gastrointestinallumen has been reviewed by us previously17 and clearly in thisstudy, as for all in vitro investigations, we simplified the in vivosituation. Nonetheless, human gastric juice was used as opposedto the usual, unphysiological, pepsin–hydrochloric acid mixture. Second, since polyphenols are present at high concentrations in tea,1,12 and are barely absorbed from the gastrointestinallumen,3 any effects on mineral speciation observed in vitro mayreasonably be anticipated in vivo.
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