In addition to their high ribosome content, rapidly growingbacteria al terjemahan - In addition to their high ribosome content, rapidly growingbacteria al Bahasa Indonesia Bagaimana mengatakan

In addition to their high ribosome

In addition to their high ribosome content, rapidly growing
bacteria also contain large amounts of other proteins associated
with translation. In particular, the most abundant protein in fastgrowing
E. coli is elongation factor Tu (EF-Tu), with about six to
seven molecules per ribosome (15), and accounting for up to
10% of the total protein mass under conditions of rapid growth
(2, 16). EF-Tu escorts charged tRNA to the ribosome and protects
it from losing its amino-acylation (17, 18). The concentration
of EF-Tu is closely linked to the concentration of tRNA,
as EF-Tu and tRNA are typically present is cells as ternary
complexes together with GTP (which activates EF-Tu) (19, 20).
EF-Tu and the 21 different tRNA synthetases (21), which charge
tRNAs with the corresponding amino acids, amount to a total
tRNA-affiliated protein mass of about two-thirds that of the ribosomal
protein mass in moderate-to-fast growth (15). As the
fraction of ribosomes allocated to making ribosomal proteins is a
central factor for cell growth, synthesizing this protein mass constitutes
a massive “investment” of cellular resources by diverting
ribosomes away from making ribosomal proteins and toward
making tRNA-affiliated proteins.
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In addition to their high ribosome content, rapidly growingbacteria also contain large amounts of other proteins associatedwith translation. In particular, the most abundant protein in fastgrowingE. coli is elongation factor Tu (EF-Tu), with about six toseven molecules per ribosome (15), and accounting for up to10% of the total protein mass under conditions of rapid growth(2, 16). EF-Tu escorts charged tRNA to the ribosome and protectsit from losing its amino-acylation (17, 18). The concentrationof EF-Tu is closely linked to the concentration of tRNA,as EF-Tu and tRNA are typically present is cells as ternarycomplexes together with GTP (which activates EF-Tu) (19, 20).EF-Tu and the 21 different tRNA synthetases (21), which chargetRNAs with the corresponding amino acids, amount to a totaltRNA-affiliated protein mass of about two-thirds that of the ribosomalprotein mass in moderate-to-fast growth (15). As thefraction of ribosomes allocated to making ribosomal proteins is acentral factor for cell growth, synthesizing this protein mass constitutesa massive “investment” of cellular resources by divertingribosomes away from making ribosomal proteins and towardmaking tRNA-affiliated proteins.
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Hasil (Bahasa Indonesia) 2:[Salinan]
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Selain konten ribosom yang tinggi, berkembang pesat
bakteri juga mengandung sejumlah besar protein lain yang terkait
dengan terjemahan. Secara khusus, protein paling melimpah di fastgrowing
E. coli adalah perpanjangan faktor Tu (EF-Tu), dengan sekitar enam sampai
tujuh molekul per ribosom (15), dan akuntansi hingga
10% dari total massa protein dalam kondisi pertumbuhan yang cepat
(2, 16). EF-Tu pendamping dibebankan tRNA ke ribosom dan melindungi
itu dari kehilangan nya amino-asilasi (17, 18). Konsentrasi
dari EF-Tu berhubungan erat dengan konsentrasi tRNA,
seperti EF-Tu dan tRNA biasanya hadir adalah sel sebagai terner
kompleks bersama dengan GTP (yang mengaktifkan EF-Tu) (19, 20).
EF-Tu dan 21 sintetase tRNA yang berbeda (21), yang biaya
tRNA dengan asam amino yang sesuai, jumlah yang total
massa protein tRNA berafiliasi sekitar dua pertiga yang dari ribosom
massa protein dalam sedang hingga cepat pertumbuhan (15). Sebagai
fraksi ribosom dialokasikan untuk membuat protein ribosom merupakan
faktor utama untuk pertumbuhan sel, sintesis protein massa ini merupakan
besar-besaran "investasi" sumber daya seluler dengan mengalihkan
ribosom dari membuat protein ribosom dan menuju
membuat protein tRNA berafiliasi.
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