RESULTS AND DISCUSSIONFive brands o

RESULTS AND DISCUSSION
Five brands of Diclofenac sodium delayed release tablets 50 mg were procured from the market and subjected to assay and comparative dissolution profile testing as per USP guidelines for determining in vitro equivalence of modified release products.
Assay of Diclofenac sodium delayed release tablets:
Twenty tablets were weighed and crushed using mortar and pestle. Quantity of powder equivalent to 100 mg of Diclofenac sodium was weighed accurately and transferred to 100 ml volumetric flask. Approximately 70 ml of methanol AR grade was added and syndicated for 15 minutes. The volume was made up to 100 ml with methanol and filtered. From the clear filtrate and aliquot equivalent to 100 ppm was pipette out and transferred to 10 ml volumetric flask. The volume was made up to 10 ml with Methanol (10 µg/ml solution).

Hasil (Bahasa Indonesia) 2:

HASIL DAN PEMBAHASAN
Lima merek Diklofenak natrium tertunda tablet rilis 50 mg yang diperoleh dari pasar dan mengalami uji dan perbandingan pengujian profil disolusi sesuai pedoman USP untuk menentukan di kesetaraan vitro produk rilis dimodifikasi.
Pengujian Diklofenak natrium tertunda tablet rilis:
Dua puluh tablet ditimbang dan hancur menggunakan lesung dan alu. Kuantitas bubuk setara dengan 100 mg natrium diklofenak ditimbang secara akurat dan ditransfer ke labu ukur 100 ml. Sekitar 70 ml metanol AR kelas ditambahkan dan sindikasi selama 15 menit. Volume dibuat sampai 100 ml dengan metanol dan disaring. Dari jelas filtrat dan aliquot setara dengan 100 ppm adalah pipet dan dipindahkan ke 10 ml labu ukur. Volume dibuat hingga 10 ml dengan Metanol (10 ug solusi / ml).