The endocrinology of the estrous cy

The endocrinology of the estrous cycle involves a delicate
balance among hormones produced by the pineal gland, hypothalamus, pituitary gland, ovaries, and endometrium. The
hypothalamus produces gonadotropin-releasing hormone
(GnRH), which is released in brief pulses into the hypothalamic-pituitary portal system, and stimulates the synthesis
and release of the gonadotropins, follicle stimulation hormone (FSH) and luteinizing hormone (LH), from the anterior pituitary gland (8). Thus, GnRH secretion elicits the release of both LH and FSH from the pituitary, but apparently
the ratio of LH/FSH reaching the circulation is influenced
by GnRH pulse frequency and by physiologic feedback from
inhibin, estrogens, and progesterone released from the ovaries. Low-frequency pulses of GnRH stimulate synthesis and
release of FSH; and high-frequency GnRH pulses stimulate
synthesis and release of LH (8). During diestrus, progesterone released from the CL suppresses the high frequency of
GnRH release. During estrus, after luteolysis occurs and circulating progesterone concentrations are low, GnRH pulse
frequency is markedly increased as the estrogens produced

Hasil (Bahasa Indonesia) 2:

The endokrinologi dari siklus estrus melibatkan halus
keseimbangan antara hormon yang diproduksi oleh kelenjar pineal, hipotalamus, kelenjar pituitari, ovarium, dan endometrium. The
hipotalamus menghasilkan gonadotropin-releasing hormone
(GnRH), yang dirilis pada pulsa singkat ke dalam sistem portal hipotalamus-hipofisis, dan merangsang sintesis
dan pelepasan gonadotropin, hormon stimulasi folikel (FSH) dan luteinizing hormone (LH), dari anterior pituitary gland (8). Dengan demikian, sekresi GnRH memunculkan rilis kedua LH dan FSH dari hipofisis, tapi rupanya
rasio LH / FSH mencapai sirkulasi dipengaruhi
oleh frekuensi denyut GnRH dan oleh umpan balik fisiologis dari
inhibin, estrogen, dan progesteron dilepaskan dari indung telur. Pulsa rendah frekuensi GnRH merangsang sintesis dan
pelepasan FSH; dan pulsa GnRH frekuensi tinggi merangsang
sintesis dan pelepasan LH (8). Selama diestrus, progesteron dilepaskan dari CL menekan tingginya frekuensi
rilis GnRH. Selama estrus, setelah luteolysis terjadi dan konsentrasi progesteron yang beredar rendah, denyut GnRH
frekuensi nyata meningkat sebagai estrogen yang dihasilkan