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SymptomsAbdominal pain that is often epigastric and described as burning,but may present as vague discomfort, abdominal fullness, orcrampingAtypical nocturnal pain that awakens the patient from sleep(especially between 12AMand 3AM)The severity of ulcer pain varies from patient to patient, and maybe seasonal, occurring more frequently in the spring or fall;episodes of discomfort usually occur in clusters lasting up to a fewweeks followed by a pain-free period or remission lasting fromweeks to yearsChanges in the character of the pain may suggest the presence ofcomplicationsHeartburn, belching, and bloating often accompany the painNausea, vomiting, and anorexia, are more common in patientswith gastric ulcer than with duodenal ulcer, but may also be signsof an ulcer-related complicationSigns Weight loss associated with nausea, vomiting, and anorexiaComplications, including ulcer bleeding, perforation, penetration,or obstructionLaboratory tests
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