ABSTRACT Oxidative stress was repor

ABSTRACT Oxidative stress was reported to be involved not only in cardiovascular diseases, but also in
hypertension. Epidemiologic studies indicated that tea consumption slightly reduces blood pressure. We conducted
two studies to determine whether black and green tea can lower blood pressure (BP) in stroke-prone
spontaneously hypertensive rats (SHRSP). Male SHRSP (n
15) were allowed to recover for 2 wk after a
transmitter for measuring BP was implanted in the peritoneal cavity. The rats were divided into three groups: the
control group consumed tap water (30 mL/d); the black tea polyphenol group (BTP) consumed water containing 3.5
g/L thearubigins,0.6 g/L theaflavins, 0.5 g/L flavonols and 0.4 g/L catechins; and the green tea polyphenol group
(GTP) consumed water containing 3.5 g/L catechins, 0.5 g/L flavonols and 1 g/L polymetric flavonoids. The
telemetry system was used to measure BP, which were recorded continuously every 5 min for 24 h. During the
daytime, systolic and diastolic BP were significantly lower in the BTP and GTP groups than in the controls. Protein
expressions of catalase and phosphorylated myosin light chain (MLC-p) were measured in the aorta by Western
blotting. GTP significantly increased catalase expression, and BTP and GTP significantly decreased MLC-p
expression in the aorta. These data demonstrate that both black and green tea polyphenols attenuate blood
pressure increases through their antioxidant properties in SHRSP. Furthermore, because the amounts of polyphenols
used in this experiment correspond to those in 1 L of tea, the regular consumption of black and green tea
may also provide some protection against hypertension in humans

Hasil (Bahasa Indonesia) 1:

Stres oksidatif abstrak dilaporkan terlibat tidak hanya di penyakit kardiovaskular, tetapi juga dalam
hipertensi. Epidemiologi penelitian menunjukkan bahwa konsumsi teh sedikit mengurangi tekanan darah. Kami dilakukan
dua penelitian untuk menentukan apakah teh hitam dan hijau dapat menurunkan tekanan darah (BP) di stroke rawan
spontan hipertensi tikus (SHRSP). SHRSP laki-laki (n 15) yang dibiarkan untuk pulih selama 2 wk setelah
transmitter untuk mengukur BP ditanamkan dalam rongga peritoneum. Tikus dibagi menjadi tiga kelompok:
kelompok kontrol dikonsumsi air keran (30 mL/d); kelompok polifenol teh hitam (BTP) dikonsumsi air yang mengandung 3.5
thearubigins g/L, theaflavins 0.6 g/L, flavonols 0,5 g/L dan Catechin 0.4 g/L; dan group
(GTP) polifenol teh hijau dikonsumsi air yang mengandung Catechin 3.5 g/L, flavonols 0,5 g/L dan flavonoid polymetric 1 g/L.
Telemetri sistem ini digunakan untuk mengukur BP, yang direkam secara terus menerus setiap 5 menit untuk 24 h. Selama
siang hari, sistolik dan diastolik BP yang secara signifikan lebih rendah dalam kumpulan BTP dan GTP daripada di kontrol. Protein
ekspresi catalase dan rantai ringan phosphorylated myosin (MLC-p) diukur dalam aorta oleh Western
blotting. GTP catalase ekspresi meningkat signifikan, dan BTP dan GTP penurunan signifikan MLC-p
ekspresi di aorta. Data ini menunjukkan bahwa kedua polifenol teh hitam dan hijau menipiskan darah
tekanan meningkat melalui mereka sifat antioksidan dalam SHRSP. Selain itu, karena jumlah polifenol
digunakan dalam percobaan ini sesuai dengan yang di 1 L teh, reguler konsumsi teh hitam dan hijau
juga mungkin memberikan perlindungan terhadap hipertensi pada manusia