Patients in whom tuberculosis is pr

Patients in whom tuberculosis is proved or strongly suspected should have treatment initiated with isoniazid,
rifampin, pyrazinamide, and ethambutol for the initial 2 months. A repeat smear and culture should be
performed when 2 months of treatment has been completed. If cavities were seen on the initial chest
radiograph or the acid-fast smear is positive at completion of 2 months of treatment, the continuation
phase of treatment should consist of isoniazid and rifampin daily or twice weekly for 4 months to complete
a total of 6 months of treatment. If cavitation was present on the initial chest radiograph and the culture at
the time of completion of 2 months of therapy is positive, the continuation phase should be lengthened to
7 months (total of 9 months of treatment). If the patient has HIV infection and the CD4
+
cell count is

Hasil (Bahasa Indonesia) 1:

Patients in whom tuberculosis is proved or strongly suspected should have treatment initiated with isoniazid,rifampin, pyrazinamide, and ethambutol for the initial 2 months. A repeat smear and culture should beperformed when 2 months of treatment has been completed. If cavities were seen on the initial chestradiograph or the acid-fast smear is positive at completion of 2 months of treatment, the continuationphase of treatment should consist of isoniazid and rifampin daily or twice weekly for 4 months to completea total of 6 months of treatment. If cavitation was present on the initial chest radiograph and the culture atthe time of completion of 2 months of therapy is positive, the continuation phase should be lengthened to7 months (total of 9 months of treatment). If the patient has HIV infection and the CD4+cell count is <100/μl, the continuation phase should consist of daily or three times weekly isoniazid and rifampin. In HIV-uninfected patients having no cavitation on chest radiograph and negative acid-fast smears at completionof 2 months of treatment, the continuation phase may consist of either once weekly isoniazid and rifapentine,or daily or twice weekly isoniazid and rifampin, to complete a total of 6 months (bottom). Patients receivingisoniazid and rifapentine, and whose 2-month cultures are positive, should have treatment extended by anadditional 3 months (total of 9 months).* EMB may be discontinued when results of drug susceptibility testing indicate no drug resistance.†PZA may be discontinued after it has been taken for 2 months (56 doses).‡RPT should not be used in HIV-infected patients with tuberculosis or in patients with extrapulmonarytuberculosis.§Therapy should be extended to 9 months if 2-month culture is positive.CXR = chest radiograph; EMB = ethambutol; INH = isoniazid; PZA = pyrazinamide; RIF = rifampin;RPT = rifapentine.

Hasil (Bahasa Indonesia) 2:

Pasien yang tuberculosis terbukti atau diduga kuat seharusnya pengobatan dimulai dengan isoniazid,
rifampisin, pirazinamid, dan etambutol untuk awal 2 bulan. Pap ulang dan budaya harus
dilakukan ketika 2 bulan pengobatan telah selesai. Jika gigi berlubang terlihat di dada awal
radiografi atau smear asam-cepat positif pada penyelesaian 2 bulan pengobatan, kelanjutan
fase pengobatan harus terdiri dari isoniazid dan rifampisin harian atau dua kali seminggu selama 4 bulan untuk menyelesaikan
total 6 bulan pengobatan. Jika kavitasi hadir pada radiografi dada awal dan budaya pada
saat penyelesaian 2 bulan terapi positif, fase lanjutan harus diperpanjang untuk
7 bulan (total 9 bulan pengobatan). Jika pasien memiliki infeksi HIV dan CD4
+
jumlah sel adalah <100 /
ml, fase lanjutan harus terdiri dari isoniazid dan rifampisin setiap hari atau tiga kali seminggu. Pada HIV
pasien yang tidak terinfeksi tidak memiliki kavitasi pada rontgen dada dan pap asam-cepat negatif pada penyelesaian
dari 2 bulan pengobatan, fase lanjutan dapat terdiri dari baik sekali isoniazid mingguan dan rifapentin,
atau harian atau dua kali isoniazid mingguan dan rifampisin, untuk menyelesaikan Sebanyak 6 bulan (bawah). Pasien yang menerima
isoniazid dan rifapentin, dan yang 2 bulan kultur positif, harus memiliki perawatan diperpanjang oleh
tambahan 3 bulan (total 9 bulan).
* EMB dapat dihentikan ketika hasil tes kerentanan terhadap obat menunjukkan tidak ada resistensi obat.
†
PZA mungkin dihentikan setelah telah diambil selama 2 bulan (56 dosis).
‡
RPT tidak boleh digunakan pada pasien terinfeksi HIV dengan TBC atau pada pasien dengan paru
TBC.
§
Terapi harus diperpanjang sampai 9 bulan jika budaya 2 bulan positif .
radiografi toraks = dada; EMB = etambutol; INH = isoniazid; PZA = pirazinamid; RIF = rifampisin;
RPT = rifapentin.