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Ethiopia ranks seventh among the world’s 22 countrieswith high tuberculosis (TB) disease burden and had anestimated incidence rate of 379 cases per 100,000 peopleper year (WHO 2008). Mycobacterium tuberculosis is themost common cause of human TB, but an unknown proportionof cases are due to M. bovis. TB caused by M. bovis(bovine tuberculosis; bTB) is clinically indistinguishablefrom TB caused by M. tuberculosis and can only be differentiatedby laboratory methods (Cosivi et al. 1998). Specificdata on zoonotic bTB transmission is very scarce in thedeveloping world because the diagnosis of TB most oftenrelays on sputum microscopy only. However, fairly recentmolecular methods like spoligotyping
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