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However, Eli Lilly continued to dominate the emerging human insulinmarket in performing R&D, surpassing major milestones during theperiod from 1980 to 1985 covered by the consent decree. Following theinitial production of human insulin through recombinant DNA techniquesin 1978, Lilly initiated clinical trials of its human insulin product, “Humalin,”in the United States in 1980, and invested in additional research facilities. In 1982, Lilly was rewarded for its efforts, receiving the firstFDA approval for human insulin in the United States. Eli Lilly was actuallymore active in filing for patents during the five-year period of thedecree than it was during the previous and subsequent five years combined.
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