A quasi-experimental design with tw

A quasi-experimental design with two treatment conditions was implemented. Participants were randomized between treatment conditions (A-CRA and A-CRA plus CM) unless otherwise considered by clinical judgment. Treatment goal regarding substance use was abstinence from cannabis and other illegal drugs in both groups. Participants who requested treatment for their CUD at the Asturias and Madrid outpatient facilities entered the study if meeting the criteria described above. Both clinical settings delivered A-CRA and A-CRA + CM. Before treatment entry, participants and responsible adults provided informed consent to enter the study. The Ethics Committee of the University of Oviedo approved this research study. All participants were evaluated at intake and post-treatment (3 months later). Urinalyses were carried out weekly during the first two weeks devoted to intake assessment and before treatment entry, and twice weekly during treatment.

This study was carried out simultaneously in two settings within the Spanish Public Health System. In Asturias, they were implemented in an outpatient setting delivering treatment for adolescents (ProgramaReciella, CESPA-Proyecto Hombre Asturias). In Madrid, at the Center for Drug Addiction belonging to MadridSalud.