of holothuria were reported to be i

of holothuria were reported to be important cartilage
building blocks and other bioactivities including antiinflammatory
and anti tumor activity properties (Herecia
and Ubeda 1998).The extract LPS obtained from Stichopus
japonicus induced inflammatory response via blocks the
MAPK signaling pathway in murine macrophages, showed
in vitro with anti-inflammatory potential Himayaa et al.
(2010). The sea cucumber Telenata ananas derived bioactive
compounds were reported to act as the chemokine
receptor subtype-5 (CCR5) with possible anti-HIV activity
Hegde et al. (2002). Potential use of sea cucumber
S. liouvillei isolated compound chondroitin sulfate (the
polysaccharides) are reported to exhibit antiviral activity
to inhibit human immunodeficiency virus (HIV) infection
(Chen 2003). Considering this as an evidence in the
present study, attempts were made to find out the bioactive
compounds from marine invertebrates such as the
Holothuria.

Hasil (Bahasa Indonesia) 1:

dari holothuria dilaporkan penting tulang rawanblok bangunan dan bioactivities lainnya termasuk antiinflamasidan anti tumor aktivitas properti (Hereciadan Ubeda 1998).LPS ekstrak yang Diperoleh dari Stichopusjaponicus diinduksi respons peradangan melalui blokMAPK menandakan jalur di tumore makrofag, menunjukkansecara in vitro dengan anti-inflamasi potensi Himayaa et al.(2010). Teripang Telenata ananas berasal bioaktifsenyawa dilaporkan untuk bertindak sebagai Kemokinreseptor subtipe-5 (CCR5) dengan aktivitas mungkin anti HIVHegde et al. (2002). Penggunaan potensi TeripangS. liouvillei diisolasi senyawa kondroitin sulfat (polisakarida) dilaporkan menunjukkan aktivitas antivirusuntuk menghambat infeksi human immunodeficiency virus (HIV)(Chen 2003). Mempertimbangkan ini sebagai bukti dalamPenelitian ini, usaha dilakukan untuk mengetahui bioaktifsenyawa dari laut invertebrata sepertiHolothuria.