Percutaneous biopsy is suited to pr

Percutaneous biopsy is suited to prove the structure
of most lesions. It is mandatory prior to any radiation
therapy or chemotherapy. The only exception
in pediatric patients is suspected malignancy in large
cartilaginous tumors, because malignant transformed
large cartilaginous tumors typically contain large benign
parts.
The choice of the biopsy needle depends on the access,
further underlying diseases (e.g., coagulopathy,
lung emphysema), and lesion size. Furthermore, the
assumed tumor entity has to be considered because
for differentiation of pediatric tumors (small, round, or
blue cell) immunohistochemical,molecular pathological,
and cytogenetic analysis has to be done apart from
histologic analysis. These complex analyses require
a certain amount of tissue, which results in the need for
a core biopsy (Hoffer 2005). Many needles are available
with selectable throw lengths. These should be
adapted to the individual lesion size and localization.
Fine-needle biopsy is only justified in recurrent tumors,
if there is malignancy, or if a sample for microbiological
analysis is obtained. For aspiration of fluid collections 22G needles are generally adequate
in neonates (Coley and Hogan 2006). Particular care
has to be taken in bone biopsy. In this case sterility has
to be guaranteed to avoid osteomyelitis.

Hasil (Bahasa Indonesia) 1:

Biopsi Percutaneous cocok untuk membuktikan strukturKebanyakan lesi. Wajib sebelum setiap radiasiterapi atau kemoterapi. Satu-satunya pengecualianpediatric pasien yang dicurigai keganasan besarTumor tulang rawan, karena berubah ganastumor besar kartilaginosa biasanya berisi besar jinakBagian.Pilihan biopsi jarum tergantung pada akses,selanjutnya mendasari penyakit (misalnya, koagulopati,emfisema paru-paru), dan ukuran lesi. Selain itu,tumor diasumsikan entitas harus dipertimbangkan karenauntuk diferensiasi tumor pediatrik (kecil, bulat, atauImunohistokimia biru sel), molekul patologis,dan cytogenetic analisis dilakukan terpisah darihistologis analisis. Analisis kompleks ini memerlukansejumlah jaringan, yang mengakibatkan perlunyabiopsi inti (Hoffer 2005). Jarum banyak tersediadengan dipilih melemparkan panjang. Ini harusdisesuaikan dengan ukuran lesi individu dan lokalisasi.Biopsi jarum halus hanya dibenarkan dalam tumor berulang,Jika ada keganasan, atau jika sampel untuk Mikrobiologianalisis yang diperoleh. Untuk aspirasi cairan koleksi 22G jarum umumnya memadaipada neonatus (Coley dan Hogan 2006). Perhatian khususharus diambil dalam tulang biopsi. Dalam kasus ini sterilitas telahdijamin untuk menghindari osteomielitis.