The most frequent adverse effects r

The most frequent adverse effects reported in patients given diclofenac systemically are gastrointestinal in nature. Typical reactions include epigastric pain, nausea, vomiting, and diarrhoea. Rarely peptic ulcer and gastrointestinal bleeding have occurred. Diclofenac has also been implicated as the causative agent in colonic ulceration,1 small bowel perforation,2 and pseudomembranous colitis.3 Diclofenac suppositories may cause local reactions such as itching, burning, or exacerbation of haemorrhoids.

Hasil (Bahasa Indonesia) 2:

Efek samping yang paling sering dilaporkan pada pasien yang diberikan diklofenak sistemik adalah gastrointestinal di alam. Reaksi khas termasuk nyeri epigastrium, mual, muntah, dan diare. Jarang ulkus peptikum dan perdarahan gastrointestinal telah terjadi. Diklofenak juga telah terlibat sebagai agen penyebab di ulserasi kolon, 1 perforasi usus kecil, 2 dan colitis.3 pseudomembran diklofenak supositoria dapat menyebabkan reaksi lokal seperti gatal, terbakar, atau eksaserbasi wasir.