diabetic patients and control subje

diabetic patients and control subjects, whereas they were
infrequently seen in the exocrine parenchyma (Fig. 2). The
extent of the T cell infiltrate in the patients with long-
standing diabetes never approached the extent that is often
termed insulitis in the islets of new-onset type 1 diabetes,
but was approximately 1.5-fold higher in patients with type
1 diabetes than in control subjects. As expected, mac-
rophages could be identified scattered in both exocrine and
endocrine tissue, but were more abundant in islets of pa-
tients with type 1 diabetes (∼two-fold) than in those of
control subjects. Macrophages were also present adjacent to
scattered beta cells in pancreatic acinar tissue in type 1
diabetes. T cells and macrophages were more commonly
present in close proximity to exocrine ducts, which had
adjacent islets, in type 1 diabetic patients than in control
subjects.
As previously reported, we frequently observed pan-
creatic fibrosis in patients with type 1 diabetes. In its
mildest form, this fibrosis was periductal only, but when
more extensive, extended to the interlobular areas. All type
1 diabetic patients had fibrosis, 40% had periductal fi-
brosis (grade 1 or 2) only, and 60% of cases had periductal
fibrosis extending to interlobular pancreas. In contrast,
only one of the control subjects had any pancreatic fibrosis
detected, which was also periductal, but was less extensive
than in any of the diabetic patients.

Hasil (Bahasa Indonesia) 2:

pasien dan subjek kontrol diabetes, sedangkan mereka
jarang terlihat di eksokrin parenkim (Gambar. 2). The
tingkat sel T menyusup pada pasien dengan panjang
diabetes berdiri tidak pernah mendekati batas yang sering
disebut insulitis di pulau baru-onset diabetes tipe 1,
tapi sekitar 1,5 kali lipat lebih tinggi pada pasien dengan tipe
1 diabetes daripada di subjek kontrol. Seperti yang diharapkan, mac
rophages dapat diidentifikasi tersebar di kedua eksokrin dan
endokrin jaringan, tetapi lebih berlimpah di pulau dari-pasien
pasien-dengan diabetes tipe 1 (~two kali lipat) dibandingkan pada mereka dari
subyek kontrol. Makrofag juga hadir berdekatan dengan
sel beta yang tersebar di jaringan asinar pankreas dalam tipe 1
diabetes. Sel T dan makrofag yang lebih umum
hadir di dekat saluran eksokrin, yang memiliki
pulau yang berdekatan, di pasien diabetes tipe 1 dibandingkan kontrol
mata pelajaran.
Seperti dilaporkan sebelumnya, kita sering mengamati pan
fibrosis creatic pada pasien dengan diabetes tipe 1. Dalam nya
bentuk paling ringan, fibrosis ini periductal saja, tapi ketika
lebih luas, diperluas ke daerah interlobular. Semua tipe
1 pasien diabetes memiliki fibrosis, 40% memiliki fi periductal
fibrosis (kelas 1 atau 2) saja, dan 60% dari kasus memiliki periductal
fibrosis memperluas interlobular pankreas. Sebaliknya,
hanya satu dari subyek kontrol punya fibrosis pankreas
terdeteksi, yang juga periductal, tapi kurang luas
daripada di salah satu pasien diabetes.