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A direct link with cell-cycle regulators has not yet been demonstrated, but based on its specific expression pattern and the stomatal phenotype of transgenic plants, it is temping to speculate that CDKB1;1 might represent a direct target of the SPCH protein. By contrast, the termination of asymmetric cell division that is required for normal stomata differentiation by the two paralogues MUTE and FAMA could also be mediated through the inhibition of CDKB1;1 activity. Further investigation is required to clarify this putative cell-cycle connection
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