The release mechanism based ondiffusion exponential of Korsmeyer-Peppa terjemahan - The release mechanism based ondiffusion exponential of Korsmeyer-Peppa Bahasa Indonesia Bagaimana mengatakan

The release mechanism based ondiffu

The release mechanism based on
diffusion exponential of Korsmeyer-Peppas
equation. The exponential (n) equation was
determined the release mechanism, fickian
diffusion (n=0.45), anamolius transport
(0.45
0/5000
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Hasil (Bahasa Indonesia) 1: [Salinan]
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The release mechanism based ondiffusion exponential of Korsmeyer-Peppasequation. The exponential (n) equation wasdetermined the release mechanism, fickiandiffusion (n=0.45), anamolius transport(0.45super case II transport (n>0.89) (Colombo etal. 2007). The mechanism release all formulashowed that the mechanism release notfollowed the Korsmeyer-Peppas equation.Exponential value less than 0.45, themechanism of release was unclassified. Themechanism release using 2 model of drugrelease because the nanocomposite of drug andclays, the composites were not occurred in theinitial time. The best kinetic models to describethe release kinetics and fitting the equationbased on goodness of fitting that the highest ofcoefficient determination (R2), the lowest ofAIC, and the lowest of RMSE that showed thesimilarity between observed data and predicteddata (equation model) (Motulsky &Chirtopoulos, 2003). The release kinetic wasdescribed by the Weibull’s model. The drugrelease linear relation can be obtained for a loglog plot of –ln (1-m) versus time (t) (Costa andLobo, 2001). Ketoprofen, sodium diclofenacand chloramphenicol succinate loaded in themesoporous of anionic clays (hydrotalcite)showed the initial burst release in 1h and the
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Hasil (Bahasa Indonesia) 2:[Salinan]
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Mekanisme rilis berdasarkan
eksponensial difusi Korsmeyer-Peppas
persamaan. Eksponensial (n) persamaan itu
ditentukan mekanisme rilis, Fickian
difusi (n = 0,45), transportasi anamolius
(0,45Super kasus II transportasi (n> 0,89) (Colombo et
al. 2007). Rilis Mekanisme semua rumus
menunjukkan bahwa rilis mekanisme tidak
diikuti persamaan Korsmeyer-Peppas.
Nilai eksponensial kurang dari 0,45, yang
mekanisme rilis adalah unclassified. The
rilis Mekanisme menggunakan 2 model obat
rilis karena nanokomposit obat dan
tanah liat, komposit tidak terjadi di
waktu awal. Model kinetik terbaik untuk menggambarkan
kinetika rilis dan pas persamaan
berdasarkan kebaikan pas yang tertinggi dari
koefisien determinasi (R2), yang terendah dari
AIC, dan terendah dari RMSE yang menunjukkan
kesamaan antara data observasi dan prediksi
data (persamaan model) (Motulsky &
Chirtopoulos, 2003). Rilis kinetik itu
dijelaskan oleh model Weibull ini. Obat
rilis linier hubungan dapat diperoleh untuk plot loglog dari -ln (1-m) terhadap waktu (t) (Costa dan
Lobo, 2001). Ketoprofen, natrium diklofenak
dan kloramfenikol suksinat dimuat dalam
mesopori dari tanah liat anionik (hidrotalsit)
menunjukkan rilis meledak awal 1h dan
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