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RESULTSIn the present work, the colon specificmicrospheres of diclofenac sodium wereprepared using solvent evaporation method. Forthe colon targeting synthetic polymers namelyethyl cellulose (EC), cellulose acetate phthalate(CAP), and Eudragit L 100-55 were used toprepare the microspheres. The preparedformulations of different drug polymer ratio wereevaluated for physical properties like particlesize, bulk density, tap density, angle of reposeand percent drug encapsulation efficiency and invitro drug release study.
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