AbstractThe sea cucumber (Holothuri

Abstract
The sea cucumber (Holothuria atra) extracts have been evaluated for the presence of bioactive compounds and
various biological activities. The methanol extracts showed anti proliferative activities against the Hela and MCF-7
cell lines. Similarly the inhibitory effects of Herpes simplex virus 1 and 2 cells were detected using the plaque reduction
assay. The extracts of H. atra were purified using the silica gel column chromatography. The active fractions collected
were observed for antimicrobial activity. The GC-MS analysis showed the availability of 59 compounds. The active
bioactive compounds found in the H. atra were analyzed and their structure was identified using the 1
HNMR and 13C NMR experiments

Hasil (Bahasa Indonesia) 1:

AbstrakEkstrak Laut mentimun (Holothuria atra) yang telah dievaluasi untuk kehadiran senyawa bioaktif danberbagai kegiatan biologis. Ekstrak metanol menunjukkan sikap anti proliferatif kegiatan terhadap Hela dan MCF-7jalur sel. Demikian pula efek penghambatan Herpes simplex virus 1 dan 2 sel terdeteksi menggunakan pengurangan plakatassay. Ekstrak H. atra ditahirkan menggunakan Kromatografi kolom silika gel. Pecahan aktif yang dikumpulkandiamati untuk aktivitas antimikroba. GC-MS analisis menunjukkan ketersediaan 59 senyawa. Aktifsenyawa bioaktif yang ditemukan di H. atra dianalisis dan struktur mereka diidentifikasi menggunakan 1HNMR dan 13C eksperimen RMN