OBJECTIVES:Previous studies have ob

OBJECTIVES:
Previous studies have obtained conflicting findings regarding possible associations between indices measuring carbohydrate intake and dyslipidemia, which is an established risk factor of coronary heart disease. In the present study, we examined cross-sectional associations between carbohydrate indices, including the dietary glycemic index (GI), glycemic load (GL), total amount of carbohydrates, and the percentage of energy from carbohydrates, and a range of blood lipid parameters.
METHODS:
This study included 1530 participants (554 men and 976 women) from 246 families within the Healthy Twin Study. We analyzed the associations using a generalized linear mixed model to control for familial relationships.
RESULTS:
Levels of the Apo B were inversely associated with dietary GI, GL, and the amount of carbohydrate intake for men, but these relationships were not significant when fat-adjusted values of the carbohydrate indices were used. Triglyceride levels were positively associated with dietary GI and GL in women, and this pattern was more notable in overweight participants (body mass index [BMI] ≥25 kg/m(2)). However, total, low-density lipoprotein and high-density lipoprotein cholesterol levels were not significantly related with carbohydrate intake overall.
CONCLUSIONS:
Of the blood lipid parameters we investigated, only triglyceride levels were positively related with dietary carbohydrate indices among women participants in the Healthy Twin Study, with an interactive role observed for BMI. However, these associations were not observed in men, suggesting that the association between blood lipid levels and carbohydrate intake depends on the type of lipid, specific carbohydrate indices, gender, and BMI.

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TUJUAN:Studi sebelumnya telah memperoleh temuan-temuan yang bertentangan mengenai kemungkinan Asosiasi antara indeks yang mengukur pengambilan karbohidrat dan dyslipidemia, yang merupakan faktor risiko penyakit jantung koroner didirikan. Dalam penelitian ini, kita akan meneliti penampang Asosiasi antara indeks karbohidrat, termasuk indeks Diet glisemik (GI), glycemic load (GL), jumlah total karbohidrat, dan persentase energi dari karbohidrat, dan berbagai parameter lipid darah.METODE:Studi ini termasuk 1530 peserta (554 pria dan wanita 976) dari 246 keluarga dalam studi Twin sehat. Kami menganalisis Asosiasi menggunakan model campuran linear umum untuk mengontrol hubungan kekeluargaan.HASIL:Tingkat b Apo terbalik dikaitkan dengan diet GI, GL dan jumlah asupan karbohidrat untuk pria, tetapi hubungan ini tidak signifikan ketika lemak-disesuaikan nilai indeks karbohidrat yang digunakan. Kadar trigliserida positif dikaitkan dengan diet GI dan GL pada wanita, dan pola ini lebih penting di peserta kelebihan berat badan (tubuh indeks massa [BMI] ≥25 kg/m(2)). Namun, total, low-density lipoprotein dan high-density lipoprotein tingkat kolesterol tidak signifikan terkait dengan asupan karbohidrat secara keseluruhan.KESIMPULAN:Parameter lipid darah kita diselidiki, hanya kadar trigliserida positif yang terkait dengan indeks diet karbohidrat antara perempuan peserta dalam studi Twin sehat, dengan peran interaktif yang diamati untuk BMI. Namun, Asosiasi ini tidak diamati pada pria, menyarankan bahwa hubungan antara tingkat lipid darah dan pengambilan karbohidrat tergantung pada jenis lipid, indeks tertentu karbohidrat, jenis kelamin, dan BMI.