Glycemic ControlDysglycemia is ofte

Glycemic Control
Dysglycemia is often conceived of as a
vasculopathic process. Preclinical ath-
erosclerosis and epidemiological studies
generally support this relationship. Clin-
ical trial data from the DCCT supplied
definitive findings strongly in favor of
beneficial effects of better glycemic con-
trol on CVD outcomes.
Glycemia is associated with preclini-
cal atherosclerosis in studies that in-
clude tests of endothelial function,
arterial stiffness, cIMT, autonomic neu-
ropathy, and left ventricular (LV) func-
tion in T1DM (16,39,126–132). The
extent of atherosclerosis by intravascu-
lar ultrasound also correlated with
HbA1c over 18 years of follow-up in the
Oslo Study; a 1% increase in mean HbA1c
was associated with a 6.4% increase in
coronary vessel stenosis (78). Intensive
DM therapy has been shown to prevent
the increase in resting heart rate charac-
teristic of patients with T1DM (133), and
autonomic function was significantly

Hasil (Bahasa Indonesia) 1:

Glycemic Control
dysglycemia is Often conceived of as a
vasculopathic process. Preclinical ath-
erosclerosis and epidemiological studies
Generally support this relationship. Clin-
ical trial of data from the DCCT supplied
de fi nitive fi ndings strongly in favor of
bene fi cial effects of better glycemic con-
trol on CVD outcomes.
Glycemia is associated with preclini-
cal atherosclerosis in studies that in-
clude tests of endothelial function,
arterial stiffness, CIMT, autonomic neuropathies
ropathy, and left ventricular (LV) func-
tion in T1DM (16,39,126-132). The
extent of atherosclerosis by intravascu-
lar ultrasound Also correlated with
HbA1c over 18 years of follow-up in the
Oslo Study; a 1% Increase in mean HbA1c
was associated with a 6.4% Increase in
coronary vessel stenosis (78). Intensive
diabetes therapy has been shown to Prevent
the Increase in resting heart rate charac-
teristic of Patients with T1DM (133), and
autonomic function was signi fi cantly