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Penyakit paru obstruktif kronik (PPOK) adalah penyebab utama kematian dan Cacat seluruh dunia.PPOK adalah penyakit pernapasan yang progresif dicirikan oleh aliran udara kronis batasan, sesak nafas (atau dyspnoea), batuk, mengi dan peningkatan produksi (lendir atau dahak) dahak. Gejala ini, dalam tertentu sesak napas, dapat membatasi kemampuan pasien untuk melakukan kegiatan sehari-hari normal. Merokok adalah penyebab dominan PPOK, 80-90% dari risiko mengembangkan penyakit paru obstruktif kronik. Penyakit yang semakin diamati pada wanita.Diagnosis dini dan pengobatan PPOK pentingPPOK memiliki dampak fisik dan emosional yang signifikan pada mereka yang menderita dari penyakit. Kronis penyakit paru obstruktif berkembang, penurunan fungsi paru-paru dari waktu ke waktu dan aktivitas fisik menjadi sangat terbatas, mengganggu kemampuan pasien untuk menjalani kehidupan penuh, campur dengan tugas-tugas sehari-hari, seperti berpartisipasi dalam rutinitas keluarga dan interaksi sosial. Diagnosis dan pengobatan dini sangat penting untuk membantu pasien tetap independen, mencegah komplikasi dan yang mengalami eksaserbasi dan meningkatkan kualitas hidup.Anticholinergics adalah fitur pertama baris rekomendasi PPOKAnticholinergics, a traditional core competence of Boehringer Ingelheim, are a first line recommendation for the management of COPD in many guidelines. Their qualities beyond bronchodilatation, i.e. improvement of dyspnoea, exercise tolerance, decreasing COPD exacerbations and improving health related quality of life for patients is the focus of ongoing modern clinical research. These improvements were to some extent already seen with short-acting anticholinergics that are marketed for a longer time, but have become greater with the more recent development of long-acting anticholinergics. In addition to these important benefits the long-acting anticholinergic tiotropium also demonstrated its ability to reduce the risk of death in the 4-year UPLIFT® trial. Further analyses from this long-term trial have shown how the clinical course of the disease can be positively affected when maintenance treatment with tiotropium is initiated as early as recommended in the GOLD Guidelines (Stage II) and have also shown the importance of initiating this treatment in patients previously naïve of maintenance therapy.The most effective intervention in COPD remains giving up smoking. Consequently smoking cessation should be standard treatment for COPD, accompanied by the usage of bronchodilators.ProductsSpiriva® (tiotropium)Maintenance treatment of patients with COPD (chronic obstructive pulmonary disease, including chronic bronchitis and emphysema), the maintenance treatment of associated dyspnoea and for prevention of exacerbations.Atrovent® (ipratropium bromide) Indicated as a bronchodilator for maintenance treatment of bronchospasm associated with chronic obstructive pulmonary disease, including chronic bronchitis, emphysema and asthma.Combivent® (ipratropium bromide/salbutamol)Indicated for the management of bronchospasms associated with reversible obstructive airway diseases in patients who require more than one bronchodilator.Berodual®Bronchodual® Duovent® (fenoterol/ipratropium bromide)For prevention and treatment of symptoms in chronic obstructive airway disorders with reversible bronchospasm, such as bronchial asthma, and especially chronic bronchitis, with or without emphysema.Devices/CFC TransitionThe Montreal Protocol and several supplementary legally binding international agreements lay down the gradual elimination of all production and use of ozone depleting substances, particularly chlorofluorocarbons (CFCs) which have been widely used as aerosol propellants. Of particular relevance to Boehringer Ingelheim is the switch from CFC-driven Metered Dose Inhalers to those propelled by the more environmentally-friendly hydrofluoroalkanes (HFAs).Boehringer Ingelheim has already launched HFA-products for their established bronchodilators Berotec®, Berodual® and Atrovent® in many countries, and has also given a lot of attention to the development of an alternative inhaler device that is propellant-free.Respimat® Soft Mist™ Inhaler
Respimat® Soft Mist™ Inhaler
The result is the Respimat® Soft Mist™ Inhaler, a highly innovative approach to inhaler technology that is designed to meet patients' needs and is also environmentally friendly. To learn more about Respimat® Soft Mist™ Inhaler we invite you to visit the global Respimat® website.
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